STRINGSTRING
BPSS2126 BPSS2126 allA allA alc1 alc1 ureA ureA ureB ureB ureC ureC allA-2 allA-2 alc2 alc2 aceB aceB tkrA tkrA BPSL2459 BPSL2459
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS2126Putative FAA-hydrolase family protein; Similar to Burkholderia cepacia 2,4-dinitrotoluene oxygenase DntG SWALL:Q8VUC7 (EMBL:AF169302) (281 aa) fasta scores: E(): 1e-27, 37.5% id in 272 aa, and to Yersinia pestis putative hydrolase ypo1566 or y2599 SWALL:Q8ZFW1 (EMBL:AJ414149) (280 aa) fasta scores: E(): 5.5e-79, 69.42% id in 278 aa, and to Brucella melitensis 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase bmei1708 SWALL:Q8YF19 (EMBL:AE009604) (301 aa) fasta scores: E(): 1.5e-72, 63.92% id in 280 aa. (282 aa)    
Predicted Functional Partners:
allA
Putative ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
     
  0.900
alc1
Similar to Ralstonia solanacearum putative allantoicase rsc3274 or rs02503 SWALL:Q8XUB7 (EMBL:AL646074) (336 aa) fasta scores: E(): 2.8e-115, 77.67% id in 336 aa, and to Schizosaccharomyces pombe probable allantoicase spac1f7.09C SWALL:ALC_SCHPO (SWALL:Q09913) (342 aa) fasta scores: E(): 5.7e-49, 44.03% id in 327 aa; Belongs to the allantoicase family.
     
  0.900
ureA
Urease gamma subunit; Similar to Bordetella bronchiseptica Urease gamma subunit UreA SWALL:URE3_BORBR (SWALL:O06705) (100 aa) fasta scores: E(): 3.3e-29, 82.82% id in 99 aa, and to Alcaligenes eutrophus Urease, structural subunit UreA SWALL:O30334 (EMBL:Y13732) (100 aa) fasta scores: E(): 1.5e-30, 85.85% id in 99 aa.
     
  0.900
ureB
Urease beta subunit; Similar to Bordetella bronchiseptica urease beta subunit UreB SWALL:URE2_BORBR (SWALL:O06707) (102 aa) fasta scores: E(): 3.2e-24, 64.35% id in 101 aa, and to Pseudomonas aeruginosa urease beta subunit UreB or pa4867 SWALL:Q9HUU6 (EMBL:AE004900) (101 aa) fasta scores: E(): 2.8e-28, 76.23% id in 101 aa.
     
  0.900
ureC
Urease alpha subunit; Similar to Synechocystis sp. urease alpha subunit UreC or sll1750 SWALL:URE1_SYNY3 (SWALL:P73061) (569 aa) fasta scores: E(): 3.3e-166, 74.86% id in 569 aa, and to Alcaligenes eutrophus urease, structural subunit UreC SWALL:O30337 (EMBL:Y13732) (570 aa) fasta scores: E(): 3.3e-185, 83.12% id in 569 aa; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
     
  0.900
allA-2
Putative ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
     
  0.900
alc2
Similar to Ralstonia solanacearum putative allantoicase rsc3274 or rs02503 SWALL:Q8XUB7 (EMBL:AL646074) (336 aa) fasta scores: E(): 4.2e-106, 74.62% id in 335 aa, and to Streptomyces coelicolor putative allantoicase sco6248 or scah10.13 or stah10.13 SWALL:ALC_STRCO (SWALL:Q9RKU4) (376 aa) fasta scores: E(): 3.3e-28, 43.82% id in 340 aa; Belongs to the allantoicase family.
     
  0.900
aceB
Similar to Escherichia coli malate synthase A AceB or Mas or b4014 SWALL:MASY_ECOLI (SWALL:P08997) (533 aa) fasta scores: E(): 1.9e-103, 50.84% id in 533 aa, and to Ralstonia solanacearum probable malate synthase A rsc1363 or rs04645 SWALL:Q8XZN2 (EMBL:AL646064) (529 aa) fasta scores: E(): 1.5e-177, 79.84% id in 531 aa.
  
 
 0.825
tkrA
Similar to Erwinia herbicola 2-ketogluconate reductase TkrA SWALL:TKRA_ERWHE (SWALL:P58000) (323 aa) fasta scores: E(): 3.7e-57, 54.79% id in 323 aa, and to Yersinia pestis putative D-isomer specific 2-hydroxyacid dehydrogenase ypo4078 SWALL:Q8Z9W1 (EMBL:AJ414160) (326 aa) fasta scores: E(): 5.6e-64, 58.51% id in 323 aa.
  
  0.811
BPSL2459
Similar to Escherichia coli 2-ketogluconate reductase TkrA SWALL:TKRA_ECOLI (SWALL:P37666) (324 aa) fasta scores: E(): 1.6e-39, 41.71% id in 326 aa, and to Ralstonia solanacearum probable dehydrogenase oxidoreductase protein rsc1034 or rs04216 SWALL:Q8Y0K9 (EMBL:AL646062) (334 aa) fasta scores: E(): 1.8e-81, 68.5% id in 327 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  0.811
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (20%) [HD]